The Future Is Here Today...Robots, Genetics, AI, Longevity, Singularity

by Aaron Saenz on August 27th, 2009

That little blue box is one of the world's smartest knees.

That little blue box is one of the world's smartest knees.

They won’t give you superhuman strength, and they definitely don’t cost six million dollars, but the artificial limbs from Ossur can think to help you walk better. The Rheo Knee, Power Knee, and Proprio Foot prosthetics all carry onboard artificial intelligences that help amputees use their bionic limbs with security and accuracy. Not only do the limbs move in a natural way and provide the strength to climb stairs foot over foot, they learn the user’s gait. Overtime, the bionic limbs will know how you walk better than you do. Check out a French demonstration video of the Power Knee after the break.

Based in Reykjavik, Iceland Ossur is a global leader in prosthetics, braces, and orthopedic education. The founder developed some of the first artificial limbs by testing them on his daughter. The new wave of bionic limbs may be drastically better than older models, but this isn’t enough for current CEO Jon Sigurdsson. His goal is to create limbs that are as good or better than the real thing. Certainly the knees and feet with artificial intelligence go a long way to helping amputees walk and run as well as their peers

Both the Rheo knee and Proprio foot (shown in image above) contain onboard computers that perform minute changes to the prosthetic to help it respond to variations in movement. The Proprio flexes to match terrain, and adjusts the ankle to fit different slopes. The Rheo adjusts actuators to control leg swing. Together, this provides the user with increased security. The embedded AIs can learn an amputees gait in just 15 steps, but continues to adjust as the user grows accustomed to the devices.

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Ten years ago, Jeff Kepner lost both his hands and feet to a bacterial infection. Today, he is recovering from the first US double hand transplant surgery. Soon, he’ll be able to hold his daughter’s hand for the first time in a decade.

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Kepner's surgery underway. Photo courtesy of University of Pittsburgh Medical Center

Kepner, a 57-year-old pastry chef living in Georgia, got his new hands after a nine-hour surgery at the University of Pittsburgh Medical Center. He is still recovering, but has strong circulation in both hands and has showed no signs of organ rejection. The success of his surgery is in part due to a unique new procedure to improve an organ’s chance of being accepted by the body.

Whenever an organ transplant takes place, doctors have to suppress the recipient’s immune system so that it does not reject the new organ outright. This suppression requires toxic drugs that can increase the chances of infection, cancer, diabetes, or other complications. But in the past decade, an innovative procedure has been used to reduce the need for such drugs while still minimizing the likelihood of rejection. Used during Kepner’s transplant, the procedure transplants stems cells from bone marrow into the donated organs, helping the immune system more quickly recognize the hands as part of the body.

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by Aaron Saenz on May 20th, 2009

It is a horrifying concept: being buried alive. Even more terrible is the prospect of living trapped in our own bodies, unable to move or communicate. It’s called locked-in syndrome. Characters like Captain Pike and Jean-Dominique Bauby, (one fictional, the other not) describe the fear and frustration of living with a healthy mind in a broken body. But there is a real-life hope. As its name suggests, Cyberkinetics’ Braingate Neural Interface device allows patients to open the door between their mind and the outside world. Utilizing years of research studying brain signals, Braingate can read impulses in the brain using tiny implanted wires and translate those impulses into commands for computer cursors, wheelchairs, and perhaps even robotic limbs.

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Braingate reads signals in the motor cortex and translates those signals into movements of a cursor on a screen.

The procedure for implanting Braingate may seem pure science fiction, but it works. Hair-thin gold wires are connected to individual neurons in the brain’s motor cortex. These wires are gathered at a small silicon array and connected to a “pedestal” embedded in the skull. This metallic interface is easy to spot (it’s a big metal nub on the top of the head). From the pedestal, signals can be sent to a computer for translation. By interpreting the motor cortex signals, scientists can determine what your brain would be trying to move (arm, hand, finger, etc) if you weren’t paralyzed.

So you have a metal nub in your head, and some wires poking into your brain, what’s the pay off?  How about the most intuitive mouse ever: by thinking about raising or lowering their hands, patients can move a cursor on the screen of a PC. Squeeze their imaginary hand, and the cursor clicks. The brain signals aren’t completely mapped out yet, and keeping track of one’s thoughts isn’t an easy task, so the cursor tends to jiggle a little and can be hard to move quickly. That being said, it allows individuals who have a hard time even blinking to be able to communicate with others and manipulate devices from their computer. Check out Kathy Hutchinson, one of the first patients, in this story from 60 minutes, the cable connected to her skull seems to be straight out of the Matrix:

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ilimb11Think you can spot an amputee?  Think again.  Meet the i-LIMB, the first commercially available prosthetic hand with five individually powered fingers.  Combining a revolutionary functionality with amazingly natural cosmetics, the i-LIMB is changing the lives of amputees across the globe – and blending right in.

Even while Dean Kamen and others we have previously reported on work on advanced robotic prostheses, the i-LIMB shows how keeping it simple can still provide amazing improvements to quality of life for amputees.   The i-LIMB uses electrodes placed on the skin of the remaining portion of the patient’s limb, usually on the top and bottom of the forearm.  When the patient moves the muscles that would normally have extended into their hand, the electrodes pick up on electrical signals generated by the muscle movement.   These signals become the basis for individual finger movement within the i-LIMB.

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Introduced in 2007 by Scottish company Touch Bionics, the i-LIMB is capable of a variety of unique grip positions that allow the user to balance power and precision as needed.  By extending the index finger alone, patients can type on a keyboard or push buttons.  The user can also grip a key or dinner plate by rotating the thumb to meet the side of the index finger.  The prosthetic is capable of stopping when a sufficient grip is achieved, allowing the patient to grip sensitive objects (e.g. a styrofoam cup) without crushing them.  These more fine-tuned features give the i-LIMB a functionality that enhances the patient’s everyday life.

Patients can choose between a number of cosmetic gloves, including amazingly lifelike skins that blend in naturally with the rest of the body.  The i-LIMB also has a modular construction that allows each finger to be detached by removing one screw.  This way, a digit needing service can be quickly swapped out for a new one, rather than leaving the patient without their prosthetic while it’s being serviced.   The i-LIMB currently costs about $18,000, and is being used by over 600 patients.  More information can be found at the Touch Bionics website.

Check out the i-LIMB in action, as reported by Voice of America:

So what’s next for Touch Bionics?  “We are shortly to release our lower profile i-LIMB Hand which is more appropriate for female and smaller male users,” says Phil Newman, Director of Marketing.  The company is also developing a product for patients missing individual fingers.  “Our next big focus is ProDigits – replacement fingers.  This is a technology for a much larger patient population which has never had a powered finger option before.  We are very excited about this and have a significant number of trial fittings in play.”

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Related to the IEEE special report on prosthetic arms is a fascinating article on prosthetic limbs that can take their signals directly from the nerves or even the brain of the user. As reported earlier, DARPA has given $30.4 million to initiate two separate prosthetic arm projects. The first project focuses on creating a noninvasive prosthetic arm and is being spearheaded by Deka as reported here. This article focuses on the second project which is aimed at connecting the user’s true intentions to the prosthetic arm either from the brain or from nerves.

One of the major problems with current prosthetic limbs is that they signal in only one direction, yet true human limbs signal on a bidirectional basis. Not only does the brain send signals to the limb to tell it what to do, but the limb sends signals back to the brain about what it is sensing in the form of pressure, temperature, and so on. The brain uses this sensory information to send adaptive instructions to the limb, allowing for the subtle or rapid changes that define true human agility. From the article:

“Sensory feedback for prosthetics is in the embryonic stages. The best mechanism on the market today consists of a vibrating motor that buzzes against the skin more or less intensely to reflect, for instance, such force factors as grip strength. The DARPA project is gunning for much more than that: researchers want an arm that transmits sensation to the user—pressure, texture, even temperature…with 100 sensors that connect the body’s natural neural signals to the mechanical prosthetic arm to create a sensory feedback loop…”

“As it turns out, the degree of control is directly proportional to the invasiveness of the method.”

The researchers are working with different levels of invasive interaction with the user, but there are two major categories of interaction.

The first category is to connect the muscles or nerve fibers that transmit signals from the brain to the limb. Even when a limb is lost, nerve fibers from the brain still exist up to the point where the limb was cutoff and amazingly they still function years after the loss of the limb. By connecting these nerve fibers to the prosthetic arm the signals from the brain to curl a finger or to clench a fist can still be accessed by interpreting the signals being transmitted across these nerve fibers. From the article:

“In a an individual with both limbs, those nerves travel from the spinal cord down the shoulder over the clavicle and then into the armpit, where they connect to about 80,000 nerve fibers that allow the brain to communicate with the arm.”

The second category is to entirely skip the nerve fibers and link directly into the neurons in the brain. From the article:

“Finally, the most extreme solution is meant for people whose bodies no longer offer any means for interfacing to the artificial limb, for whom even nerve-rerouting surgery may not be an option”

“When electrodes penetrate directly into the motor cortex, embedded electronic circuits intercept the motor neurons firing their instructions and, with the help of complex algorithms, translate the related signals into a language that can control the mechanics of the arms.”

by Keith Kleiner on July 29th, 2008

In Feb 2008 IEEE Spectrum released a fantastic special report on some of the latest work being done on prosthetic arms.

The special report covers a lot of ground, but mostly focuses on DARPA’s Revolutionizing Prosthetics program:

“The program was created in 2005 to fund the development of two arms. The first initiative, the four-year, US $30.4 million Revolutionizing Prosthetics contract, to be completed in 2009, led by Johns Hopkins Applied Physics Laboratory in Laurel, Md., seeks a fully functioning, neurally controlled prosthetic arm using technology that is still experimental. The latter, awarded to Deka Research and Development Corp., Kamen’s New Hampshire–based medical products company (perhaps best known for the Segway), is a two-year $18.1 million 2007 effort to give amputees an advanced prosthesis that could be available immediately “for people who want to literally strap it on and go.” Kamen’s team designed the Deka arm to be controlled with noninvasive measures, using an interface a bit like a joystick.”

Because there are only about 6,000 prosthetic arms needed per year, the market has not been big enough to justify the large investment required to make next generation prosthetic arms. As a result it is amazing to note that commercially available prosthetic arm technology has not changed much in 100 years and is stuck in the “stone age”! Meanwhile prosthetic legs have seen significant investment and are extremely advanced and capable today.

The DARPA funding has literally changed the game by providing the investment necessary to propel prosthetic arms into the current era and beyond. In subsequent posts I will highlight some of the more notable aspects of this report.