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CRISPR


Latest significant advancements in CRISPR research. Reporting on the far-reaching impacts of CRISPR on society and humanity.

New Study Is the Most Successful Attempt to Gene Edit Human Embryos So Far

In the quest for CRISPR supremacy, China just won another first. Last week, a team used CRISPR-Cas9 to correct a single mistaken DNA letter in over a dozen human embryos—and succeeded 16 out of...

Newly-Decoded Wheat Genome Opens the Door to Engineering Superfoods

Tweaking the DNA of crops to make them hardier and more productive is one of the most promising applications of gene-editing technology. That’s not been possible with wheat because its complex genome has proved...

New Study Sounds a Note of Caution in the Development of CRISPR Gene Therapies

The discovery of CRISPR gene editing technology led many to believe we may soon be able to tweak our DNA with ultra-high accuracy. But a new study has found it can cause more unintended...

New DNA Synthesis Method Could Soon Build a Genome in a Day

Synthetic biologists are the computer programmers of biology. Their code? DNA. The whole enterprise sounds fantastical: you insert new snippets of DNA code—in the form of a chain of A, T, C, G letters—into an...

Three Huge Ways Tech Is Overhauling Healthcare

We are on the brink of a revolution in healthcare. AI is making the drug discovery process >100X faster and cheaper, and 90 percent more likely to succeed in clinical trials. Mobile health is...

What Makes People Distrust Science? Surprisingly, Not Politics

Today, there is a crisis of trust in science. Many people—including politicians and, yes, even presidents—publicly express doubts about the validity of scientific findings. Meanwhile, scientific institutions and journals express their concerns about the...

The Epic Project to Record the DNA of All Life on Earth

Advances in biotechnology over the past decade have brought rapid progress in the fields of medicine, food, ecology, and neuroscience, among others. With this progress comes ambition for even more progress—realizing we’re capable of, say,...

Living Neanderthal ‘Mini-Brains’ May Reveal What Makes Our Brains Special

He isolated DNA from Egyptian mummies. He discovered the Denisovans, an extinct ancient human species, by sequencing DNA from a tiny bone fragment. He led a massive study that reconstructed the Neanderthal genome—and found...

Scientists Kick Off Synthetic Biology Project to Make Virus-Resistant Super Cells

Recently, roughly 200 eminent scientists assembled in Boston. Their agenda? Creating “superhero” human cells impervious to all viral attacks and possibly other killers—radiation, freezing, aging, or even cancer. The trick isn’t super-soldier serum. Instead, the...

This New Startup Will Use CRISPR as a Search Engine to Hunt Down Diseases

By now, you’ve heard of CRISPR—the bacterial self-defense mechanism that can be used to modify the genome. From “biohackers” building the hype by injecting themselves with CRISPR—and later regretting it—to the more measured, successful...

CRISPR-on-a-Chip For Diagnosing Cancer May Soon Be a Thing

Oh CRISPR, how you’ve grown. From an obscure part of the bacterial immune defense system, you’re now on track to cure genetic diseases, thwart superbugs, boost global food production, and wipe out disease-carrying pests. And...

Not Just Gene Editing—CRISPR Toolkit Expands With Trio of New Tricks

CRISPR, the superhero of gene editing, just got a little more super. In a trio of studies released last week in Science, leading CRISPR labs around the world unveiled some ultra-creative additions to the technique,...

New CRISPR Method Takes on Duchenne Muscular Dystrophy

The advance of CRISPR gene editing technology, which uses an RNA strand to guide an enzyme called Cas9 to cut a specific portion of DNA, has raised concerns and sparked debate as people envision...

Why Gene Silencing Could Launch a New Class of Blockbuster Drugs

Long before CRISPR, there was gene silencing. Ever since the Human Genome Project transcribed our genetic bible in 1997, scientists have dreamt of curing inherited diseases at the source. The first audacious idea? Shoot the...

Gene Therapy Had a Breakthrough 2017—2018 May Be Even Better

Gene therapy had a hell of a 2017. After decades of promises but failed deliveries, last year saw the field hitting a series of astonishing home runs. The concept of gene therapy is elegant: like...

New Research Suggests Immunity to CRISPR Gene Editing Poses a Challenge

CRISPR-Cas9 is the talk of the town in biotechnology. There is a huge amount of public interest in the possibilities provided by this new genome editing technology, and many are hoping CRISPR could eventually...
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How Neuroscience Is Beginning to Rewire the Brain From the Inside Out

In an interview at Exponential Medicine in San Diego, Singularity University faculty and speaker Dr. Divya Chander takes a look at how emerging technologies are letting us peer inside the human brain like never before. As an anesthesiologist...

The Enormous Promise and Peril of Bioengineering’s Pandora’s Box

We’re standing on the threshold of extraordinary capability in synthetic biology. CRISPR-Cas9, the genome editing technique discovered in 2014, is at the forefront of this newfound potential for innovation. These advancements provide an opportunity...

CRISPR Can Now Hitch a Ride on Nanoparticles to Battle Disease

It started like any other day. Dr. Hao Yin walked into the lab at MIT, ready to check on his transgenic mice. He had no idea he was about to make history. Yin’s mice harbored...
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You’ve Heard All About CRISPR Gene Editing—Here’s How It Works

Gene editing is in the news a lot these days, but what is it exactly? Gene editing is the process of making precise and permanent changes to living things at the level of DNA,...
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Do We Have the Right to Edit the Genes of an Entire Species?

Scientists can now more cheaply and efficiently edit animal and human DNA using the CRISPR/Cas9 gene editing system. But should we edit species, and if so, to what extent? An interesting way to consider this question...
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Tech-X-Planations | Introducing a New Original Weekly Video Series

We’ve all name-dropped a new technology that sounds awesome—like CRISPR/Cas9—without really knowing the basics. This is why we’ve created Tech-x-planations, Singularity Hub’s new weekly video series that explores fundamental ideas in science, technology, and the...

The Era of Human Gene Editing Is Here—What Happens Next Is Critical

Scientists in Portland, Ore., just succeeded in creating the first genetically modified human embryo in the United States, according to Technology Review. A team led by Shoukhrat Mitalipov of Oregon Health & Science University is reported to “have...

A Living Hard Drive: This GIF Was Stored in the DNA of Bacteria

DNA is a hugely promising medium for storing data. Consider that a cell nucleus can hold the instructions for an organism as complex as a human. So far efforts to store non-genetic data in...

Designer Babies Dilemma in Sharp Focus With Fast Moving Fertility Tech

Moral panic around “designer babies” is nothing new, but rapid advances in technology that allows adult cells to be reprogrammed into sperm and egg cells could bring the issue into sharp focus. Since the 90s...

What Happens When Tech Takes Control of Evolution?

Over the span of a few billion years, diversity of life has flourished on Earth through the process of natural selection. Then, not long ago (relatively), human intelligence evolved. For the first time one species,...

Lung Cancer Patient First to Undergo CRISPR Gene Editing

The CRISPR-Cas9 “drag-and-drop” gene editing technique has been used in its first human trial, reports Nature. Scientists at Sichuan University in Chengdu, China began a trial last month to treat a lung cancer patient....

Medicine Will Advance More in the Next 10 Years Than It Did in the Last 100

Mark Zuckerberg and his wife, Priscilla Chan, recently announced a $3 billion effort to cure all disease during the lifetime of their daughter, Max. Earlier this year, Silicon Valley billionaire Sean Parker donated $250...

Designer Babies and the New Technology of Having Children

Recently, we looked at how exponential tech impacts sex and dating. In this post, we'll look at: Reproduction without sex Freezing your eggs to extend your reproductive timeline Designer babies Making babies without eggs Imagine a...

Scientists Hoped to Have Cloned a Living Woolly Mammoth by Now — Why Haven’t We?

Five years ago, we wrote about a team of Japanese scientists who predicted they would successfully clone a woolly mammoth within five years. So, why don't we have a living mammoth yet? Even though the...

This Is the Olympics On Technology—When Enhancement Is the Norm

For the purpose of this post, I'd like to suspend moral and ethical considerations for a moment — let’s call this a fun thought experiment. As we enter Olympics season, I find myself thinking about what...

Ray Kurzweil Predicts Three Technologies Will Define Our Future

This is the last in a four-part series looking at the big ideas in Ray Kurzweil's book The Singularity Is Near. ​Be sure to read the other articles: Will the End of Moore’s Law Halt...

CRISPR Dispute Raises Bigger Patent Issues That We’re Not Talking About

The worlds of science, technology and patent law eagerly await the U.S. government’s decision on who deserves patents on what many have referred to as the biotechnology invention of the century: the CRISPR/Cas9 gene-editing...

As Technology Barrels Ahead—Will Ethics Get Left in the Dust?

The battle between the FBI and Apple over the unlocking of a terrorist’s iPhone will likely require Congress to create new legislation. That’s because there really aren’t any existing laws which encompass technologies such...

UK Will Use CRISPR on Human Embryos — a Step Closer to Human Genome Editing

"It is human nature and inevitable in my view that we will edit our genomes for enhancements.” —J. Craig Venter This week, Kathy Niakan, a biologist working at the Francis Crick Institute in London received the...

CRISPR/Cas9 Genome Editing Is a Huge Deal, But It’s Just the Tip of the Iceberg

CRISPR/Cas9 has been touted as an almost magical technology in the news—and rightly so. The technique allows scientists to alter the DNA of living cells and, it’s hoped, achieve a longstanding goal of science...

10 Most Exciting SciTech Advances of 2015

As we near the end of 2015, here are my top 10 picks for 2015 technology breakthroughs. These genius inventions are sending us careening into a world of abundance, bold visionaries and accelerating exponential change. My...

A Big Year for Biotech: Bugs as Drugs, Precision Gene Editing, and Fake Food

Speculations around whether biotech stocks are in a bubble remain undecided for the second year in a row. But one thing stands as indisputable—the field made massive progress during 2015, and faster than anticipated. For...

Gene Drives Could Wipe Out Insect-Borne Disease — But What’s the Price?

In 2014, a few days after Christmas, Dr. Valentino Gantz walked into his lab at the University of California, San Diego to check on some newly hatched fruit flies. With a single look, he knew...

Exponential Medicine: What to Expect When You’re Expecting Designer Babies

Anywhere you look in the modern world, you’ll see humans translating science fiction into science fact. We make predictions about a far off future, and then our curiosity drives us to make it reality—whether...

A Genomics Revolution: Evolution by Natural Selection to Evolution by Intelligent Direction

Humanity is moving from evolution by natural selection (Darwinism) to evolution by intelligent direction. For most of human history, our average age was only about 26 years old. We would procreate at age 13, live just...

Gene Editing Is Now Cheap and Easy—and No One Is Prepared for the Consequences

In April 2015, a paper by Chinese scientists about their attempts to edit the DNA of a human embryo rocked the scientific world and set off a furious debate. Leading scientists warned that altering...

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